KMID : 1141820170170020173
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Journal of Gastric Cancer 2017 Volume.17 No. 2 p.173 ~ p.179
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Botulinum Toxin Injection for the Treatment of Delayed Gastric Emptying Following Pylorus-Preserving Gastrectomy: an Initial Experience
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Lee Jung-Hwan
Kim Chan-Gyoo Kim Young-Woo Choi Il-Ju Lee Jong-Yeul Cho Soo-Jeong Kim Young-Il Eom Bang-Wool Yoon Hong-Man Ryu Keun-Won
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Abstract
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Purpose: To report our experience of endoscopic botulinum toxin injection in patients who experienced severe delayed gastric emptying after pylorus-preserving gastrectomy (PPG).
Materials and Methods: We reviewed the medical records of 6 patients who received the botulinum toxin injection. They presented with severe delayed gastric emptying in the early postoperative period. Endoscopic botulinum toxin was administered as 4 injections of 25?50 IU into each of the 4 quadrants of the prepyloric area.
Results: All botulinum toxin injections were successful without any complications, enabling 5 patients to tolerate soft solid diets and one to tolerate a soft fluid diet within 10 days. The endoscopic criteria of 4 patients improved. Symptom recurrence caused 2 patients to undergo repeat injections that were successful. The median follow-up period was 27 months, and all patients could ingest normal regular diets at the last follow-up.
Conclusions: Endoscopic botulinum toxin injection is a feasible treatment option for early delayed gastric emptying after PPG.
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KEYWORD
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Surgery, Gastric stasis, Gastrectomy, Complications, Endoscopy, Botulinum toxins
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